OrganoCatalysts

We provide cinchona-amine based catalysts for different types of organocatalysis.The amino-cinchonas and squaramide-conchonas (very powerful catalysts) can be used for asymmetric Michael additions and other important transformations.We are commercializing a series of very useful picolinamide-cinchona catalysts that are used for the asymmetric hydrosilylation of ketimines, to give chiral amines in very high enantioselectivities. Please see:Eur. J. Org. Chem.,7339-42.DOI:10.1002/ejoc.201403180. These can also be immobilized using the technology described in:Molecules,2016,21, 1182(1-9)http://www.mdpi.com/1420-3049/21/9/1182 and WO2015052656. These can also be used in flow-chemistry; see:https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1916-4858